Table A1.
Extramedullary Disease Assessment
| Site | E1479, E3480 (n = 328) | E3999 (n = 422) | E1900 (n = 644) | Others (n = 1,847) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | PE | BX | Other | No. | C | P | No. | Inv | No. | C | P | |
| CNS | 324 | 7 | 0 | 3 | — | — | — | 644 | 6 | — | — | — |
| Peripheral nervous system | 327 | 6 | 0 | 2 | — | — | — | 644 | 0 | — | — | — |
| Leukemic meningitis | — | — | — | — | 397 | 0 | 0 | — | — | 1,399 | 5 | 11 |
| Liver | 326 | 41 | 0 | 11 | 416 | 9 | 0 | — | — | 1,748 | 112 | 0 |
| Spleen | 326 | 56 | 0 | 4 | 412 | 23 | 0 | 644 | 3 | 1,745 | 151 | 0 |
| Nodes | 325 | 68 | 4 | 0 | — | — | — | — | — | — | — | — |
| Mediastinal nodes/mass | — | — | — | — | 398 | 5 | 0 | 644 | 2 | 1,740 | 14 | 0 |
| Peripheral nodes | — | — | — | — | 415 | 15 | 1 | — | — | 1,796 | 247 | 10 |
| Gingival hypertrophy* | 322 | 55 | 411 | 17 | 0 | 642 | 32 | — | — | — | ||
| Cranial nerve palsy | — | — | — | — | 411 | 0 | 0 | — | — | — | ||
| Skin | 325 | 28 | 2 | 0 | 416 | 11 | 2 | 643 | 7 | 1,810 | 75 | 21 |
| Other | 285 | 15 | 2 | 4 | 367 | 7 | 2 | 622 | 15 | 1,199 | 79 | 10 |
NOTE. Dashes indicate terms not appearing on forms.
Abbreviations: BX, biopsy; C, clinically positive or involved; Inv, involved; No., number of responses to the question on the form; Other, x-ray, scan, or chemical; P, pathologically positive or involved; PE, physical examination.
*
For E1479 and E3480, gingival hypertrophy appeared as a symptom and not as a site of extramedullary disease; shown is the number of patients with symptoms present. For other studies in particular, comments were reviewed to elicit details about extramedullary disease coded as other; these were recoded in the appropriate category where possible.