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. 2016 Aug 18;22(42):14940–14949. doi: 10.1002/chem.201602697

Figure 1.

Figure 1

Formation and hydrolysis of mixed anhydrides from oxazolone 1 and phosphate esters monitored by the evolution of HPLC peak areas (%); (a) formation and hydrolysis of mixed anhydride 3 a in a 50 mm pH 6.5 methyl phosphate (2 a) aqueous buffer (filled circles); (b) similar reaction of oxazolone 1 and hydrolysis of 3 c in a pH 6.5 buffer prepared from 50 mm phosphate ester 2 c (open circles).