Fig 3. Effects of dexmedetomidine on isoflurane-induced changes in expression of apoptosis-related proteins.
Representative Western blots (A) showing levels of cleaved caspase-3, BAD, Bcl-2 and BDNF in hippocampus at 19d after animals were treated as described in Fig 2. Levels of caspase-3 (B), BAD (C), Bcl-2 (D) and BDNF (E) were quantitated relative to that of β-actin. Data are represented as mean ± SD (n = 8). *P < 0.05 vs. control group; #P< 0.05 vs. ISO group; &P< 0.05 vs. DEX group.