TABLE 2.
Wild-type allele | Mutant allele | |
---|---|---|
n | 359 | 22 |
Age (years) | 42±3.1 | 40±6 |
Etiology (%) | ||
Dilated cardiomyopathy | 94.27 | 100 |
Functional class (% NYHA III/IV) | 67.2 | 66.66 |
LVEF (%) | 24.5±8 | 22±9 |
Polymorphism numbering is based on using the GenBank accession number AF177763.1 for human PLN sequence, corresponding to proximal promoter and exon 1 as a reference.
DCM, dilated cardiomyopathy; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association Classification.