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. Author manuscript; available in PMC: 2016 Oct 21.
Published in final edited form as: Hum Mutat. 2008 May;29(5):640–647. doi: 10.1002/humu.20692

TABLE 2.

Clinical Characteristics of Dilated Cardiomyopathy Patients With the −36A>C Substitution in the PLN Gene*

Wild-type allele Mutant allele
n 359 22
Age (years) 42±3.1 40±6
Etiology (%)
 Dilated cardiomyopathy 94.27 100
 Functional class (% NYHA III/IV) 67.2 66.66
 LVEF (%) 24.5±8 22±9
*

Polymorphism numbering is based on using the GenBank accession number AF177763.1 for human PLN sequence, corresponding to proximal promoter and exon 1 as a reference.

DCM, dilated cardiomyopathy; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association Classification.