Figure 9.
Changes in α-smooth muscle actin (αSMA) in liver sections and in LX2 cells. (a) Immunostaining of αSMA on sections of wild type (Wt) and decorin-null (Dcn−/−) livers after 4 months of TA-exposure and at the end of the regression period (TA4+4). (b) Immuncytochemistry of αSMA performed on cells transfected with scrambled (scr) siRNA or with siRNA specific for decorin (siDcn) in the absence or presence of TGFβ1 for 48 h. αSMA is shown as red and nuclei are counterstained with DAPI. Scale bar = 100 μm for each picture.