Skip to main content
. 2016 Oct 21;11(10):e0165093. doi: 10.1371/journal.pone.0165093

Fig 4. The effect of rLj-RGD3 on infarct volume in the brains of focal cerebral ischemia/reperfusion rats.

Fig 4

a, b, c, d, e, f and g in panel A represent the sham group, the VT group, the rLj-RGD3 100.0 μg·kg-1 group, the rLj-RGD3 50.0 μg·kg-1 group, the rLj-RGD3 25.0 μg·kg-1 group, the Edaravone 1.5 mg·kg-1 group, and the Eptifibatide 100.0 μg·kg-1 group, respectively. TTC is a fat-soluble, light-sensitive complex. Normal tissue becomes red when dehydrogenase reacts with TTC. In contrast, ischemic tissue appears white because it lacks dehydrogenase. The greatest infarct volumes (approximately 40%) were observed in the VT group, and the infarct volumes were approximately 35% lower in the high-dose rLj-RGD3 group (**p <0.01 vs. the VT group). The data are shown as the means ± SD, n = 6.