Table 4.
Suggestive Associations with Sleep SpO2
| SNP | B37 Region | SNPs in Region | Genes in Region | N | CAF | β (SE) BMI Adjusted | β (SE) BMI Unadjusted | P Value | Direction |
|---|---|---|---|---|---|---|---|---|---|
| rs75108997 A | 1q42:233,947,565–233,954,231 | 4 | 11,809 | 0.013/0.014/NA | −0.291 (0.055) | −0.296 (0.058) | 1.40 × 10−7 (3.52 × 10−7) | −−? | |
| rs116133558 T | 1q32:203,716,843 | 1 | ATP2B4 | 11,351 | 0.014/NA/NA | 0.291 (0.056) | 0.231 (0.059) | 2.18 × 10−7 (9.09 × 10−5) | +?? |
Definition of abbreviations: BMI = body mass index; CAF = coded allele frequency; NA = not available; SNP = single-nucleotide polymorphism; SpO2 = average percentage of oxyhemoglobin saturation.
P values in parentheses were obtained from equivalent BMI-unadjusted model results. CAF and direction columns are ordered from left to right as Hispanic Community Health Study/Study of Latinos, Multi-Ethnic Study of Atherosclerosis, and Starr County Health Studies.