Table 1.
≥Baseline Characteristics by SCD status
| SCD | No SCD | |
|---|---|---|
| Number | 205 | 12865 |
| Age | 59.6 (5.5) | 56.9 (5.7) |
| Male (%) | 136 (66) | 5599 (44) |
| African American (%) | 83 (40) | 3160 (25) |
| Education | ||
| Advanced | 55 (27) | 4754 (37) |
| Intermediate | 66 (32) | 5283 (42) |
| No or Basic | 83 (41) | 2709 (21) |
| Current drinking (%) | 96 (47) | 7287 (57) |
| Current smoking (%) | 73 (36) | 2799 (22) |
| Diabetes mellitus (%) | 83 (40) | 1853 (14) |
| Hypertension (%) | 131 (64) | 4520 (35) |
| Coronary heart disease (%) | 72 (36) | 679 (5) |
| Heart failure (%) | 29 (14) | 597 (5) |
| Systolic blood pressure (mmHg) | 132.2 (25.6) | 121.2 (18.6) |
| Diastolic blood pressure (mmHg) | 73.5 (12.5) | 72.2 (10.3) |
| Body mass index (kg/m2) | 28.9 (5.6) | 28.0 (5.4) |
| Heart Rate (bpm) | 68.7 (12.8) | 65.9 (10.0) |
| Cornell Voltage (uV) | 1625 (763) | 1237 (548) |
| LDL cholesterol (mg/dL) | 143.5 (43.4) | 133.2 (36.7) |
| HDL cholesterol (mg/dL) | 41.7 (13.1) | 49.7 (16.8) |
| eGFRcr category (%) | ||
| ≥ 90 | 107 (52) | 9394 (73) |
| 60–89 | 73 (36) | 3231 (25) |
| 45–59 | 16 (8) | 172 (1.3) |
| <45 | 9 (4) | 68 (0.5) |
| eGFRcr (ml/min/1.73 m2) | 86.9 (22.2) | 96.6 (15.6) |
| eGFRcr-cys (ml/min/1.73 m2) | 81.2 (23.1) | 95.4 (16.9) |
| eGFRcys (ml/min/1.73 m2) | 75.0 (23.8) | 91.0 (18.2) |
| Cystatin C (mg/L) | 1.11 (0.51) | 0.88 (0.29) |
| β2-microglobulin (mg/L) | 2.6 (2.0) | 2.0 (1.4) |
Data are presented as mean (SD), n (%). eGFRcr indicates estimated GFR based on serum creatinine; eGFRcr-cys, eGFR based on creatinine and cystatin C; eGFRcys, eGFR based on cystatin C.