Figure 2.

Positive correlation between serum MIF levels and levels of the inflammatory markers CRP (A), ESR (B), disease activity (BVAS, C), and serum MPO-ANCA titers (D) in patients with MPA. Serum samples were collected from patients with MPA during both the active and inactive disease states. Serum MIF was assayed by ELISA. Each point represents a sample collected from a different MPA patient.

Abbreviations: BVAS, Birmingham Vasculitis Activity Scores; CRP, C-reactive protein; ELISA, enzyme-linked immunosorbent assay; ESR, erythrocyte sedimentation rate; MIF, migration inhibitory factor; MPA, microscopic polyangiitis; MPO-ANCA, myeloperoxidase–antineutrophil cytoplastic antibody.