Figure 1.

Linkage diagram showing potential genetic associations with several autoimmune diseases. Copyright © 2007, National Academy of Sciences U.S.A. Adapted with permission from Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabasi AL. The human disease network. Proc Natl Acad Sci U S A. 2007;104:8685–8690.

Abbreviations: MS, multiple sclerosis; BLS, bare lymphocyte syndrome; AML, acute myelogenous leukemia; GVHD, graft vs host disease; HIV, human immunodeficiency virus; PDD, platelet defect deficiency; IDDM, insulin-dependent diabetes mellitus; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; RUNX1, runt-related transcription factor 1; CIITA, Class II, major histocompatibility complex, transactivator; IL-10, interleukin 10, PTPN22, protein tyrosine phosphatase nonreceptor 22.