Table 1:

Summary of recommended acquisition parameters for DSC perfusion imaging

Acquisition Parameter	Recommendation
Pulse sequence	Generally GRE-EPI rather than SE-EPI
TR	1.0–1.5 seconds (SE-EPI); minimum (vs “as short as possible”) for GRE-EPI; generally 1.0–1.5 seconds
TE	40–45 ms at 1.5T; 25–35 ms at 3T
Flip angle	60°–70°
Temporal coverage	120 Time points
Preload Gd-based contrast agent dose (particularly for studies performed with a high flip angle)	One-fourth to single dose (0.025–0.1 mmol/kg Gd), given 5–10 minutes prior to dynamic imaging
Slice thickness	3–5 mm
Matrix	128 × 128 (range, 64 × 64 to 256 × 256)
FOV	20 × 20 cm (range, 20 × 20 to 24 × 24 cm)
IV catheter gauge	18- to 20-ga antecubital IV, right arm preferred
Injection rate	3–5 mL/s
Total acquisition time	Approximately 2 minutes

Note:—Gd indicates gadolinium.