Table 1. Characteristics of Patients With Upper Gastrointestinal Hemorrhage, Criterion-Classified into Three Severity Levels.
Patient characteristics | Mild | Moderate | Severe | P-value* |
---|---|---|---|---|
n = 255 mean ± SD |
n = 664 mean ± SD |
n = 124 mean ± SD |
||
Demographics | ||||
Male (n, %) | 175 (68.6) | 427 (64.3) | 87 (70.2) | 0.871 |
Age (year) | 54.6 ± 18.0 | 60.4 ± 14.8 | 58.4 ± 14.2 | 0.010 |
Mode of presentation (n, %) | ||||
Hematemesis | 117 (45.9) | 299 (45.0) | 66 (53.2) | 0.315 |
Coffee ground vomiting | 67 (26.3) | 114 (17.2) | 26 (21.0) | 0.048 |
Hematochezia | 20 (7.8) | 40 (6.0) | 8 (6.5) | 0.462 |
Melena | 113 (44.3) | 421 (63.4) | 69 (55.7) | 0.001 |
Syncope | 28 (11.0) | 144 (21.7) | 34 (27.4) | < 0.001 |
Hemodynamics | ||||
Pulse (/min) | 89.8 ± 16.3 | 91.4 ± 15.7 | 93.1 ± 17.7 | 0.022 |
SBP (mmHg) | 128.6 ± 21.6 | 120.6 ± 20.5 | 88.5 ± 17.0 | < 0.001 |
Biochemicals | ||||
Hemoglobin (g/dL) | 11.4 ± 2.4 | 7.0 ± 2.1 | 7.4 ± 2.9 | < 0.001 |
BUN (mg/dL) | 23.9 ± 16.5 | 36.5 ± 21.7 | 37.6 ± 22.5 | < 0.001 |
Co-morbidities (n, %) | ||||
Cirrhosis | 14 (5.5) | 106 (16.0) | 28 (22.6) | < 0.001 |
Hepatic failure | 0 (0) | 6 (0.9) | 2 (1.6) | 0.071 |
Cardiac failure | 1 (0.4) | 6 (0.9) | 4 (3.2) | 0.024 |
Renal failure | 4 (1.6) | 53 (8.0) | 12 (9.7) | < 0.001 |
Clinical outcomes (n, %) | ||||
Re-bleeding | 6 (2.4) | 42 (6.3) | 18 (14.5) | < 0.001 |
Dead | 0 (0) | 1 (0.2) | 24 (19.4) | < 0.001 |
*P-value from chi-squared for linear trends, or two-way ANOVA by rank. SD: standard deviation; SBP: systolic blood pressure; BUN: blood urea nitrogen.