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. Author manuscript; available in PMC: 2016 Oct 21.
Published in final edited form as: J Immunol. 2016 Jan 29;196(5):2031–2040. doi: 10.4049/jimmunol.1501239

FIGURE 1.

FIGURE 1

NOD mice show higher expression of type 1 IFN in response to CpG. Type 1 IFN levels were measured 6 h post-CpG stimulation by ELISA in serum samples of NOD and B6 mice 6 h post CpG treatment (A), culture supernatant of enriched-splenic DC culture (B), and culture supernatant of Flt3L-BMDC (C). (D) Type 1 IFN gene expression in CD11c+-enriched population measured by quantitative PCR. Data presented in this paper are from one of at least two to four independent experiments. Comparisons were made between NOD and B6 (A and B) or B6g7 (C and D). *p < 0.05, **p < 0.01.