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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Hepatology. 2016 Sep 26;64(5):1652–1666. doi: 10.1002/hep.28774

Figure 4. Recombinant Wnt7A protein induces expression of biliary markers in vitro through activation of β-catenin.

Figure 4

(A) Expression of EpCAM and Sox9 is increased in AML12 cells treated with recombinant human Wnt7A. (B) Sox9 expression is significantly increased in Hep3B cells treated with recombinant human Wnt7A. (C) Treatment of Hep3B cells with recombinant human Wnt7A increases TOPflash reporter activity. *-p<.05; ***-p<0.001