Skip to main content
. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Neurosci Biobehav Rev. 2016 Jul 25;70:271–287. doi: 10.1016/j.neubiorev.2016.07.024

Table 4.

Meta-Analytic Results for Linear and Quadratic Effect of Age on White Matter Microstructure of Anterior Thalamic Radiation

Model # Studies # Models Age Range Beta (Age) p Beta (Age2) p R2 Adjusted R2 SSE
FA
Linear 7 9 1–90 −0.7 .001 - - 0.272 0.251 225.691
Quadratic 7 9 1–90 0.903 .001 −1.616 .001 0.431 .412 176.459*
Linear 7 9 10–20 0.168 .001 - - 0.842 0.824 9.55
Quadratic 7 9 10–20 0.588 .218 −0.422 .377 0.843 .824 9.459
MD - Only 1 study reported regression coefficients corresponding to age effect on MD
AD
Linear 3 4 1–40 −0.807 .001 - - 0.536 0.517 46.401
Quadratic 3 4 1–40 0.508 .052 −1.351 .001 0.638 0.62 36.162*
Linear 3 4 10–20 −0.655 .001 - - 0.467 0.411 2.969
Quadratic 3 4 10–20 0.836 .516 −1.499 .248 0.486 0.417 2.862
RD
Linear 3 4 1–40 −0.672 .001 - - .372 0.347 62.764
Quadratic 3 4 1–40 −1.092 .002 0.432 .201 0.383 0.351 61.72
Linear 3 4 10–20 −0.216 .005 - - 0.805 0.785 4.285
Quadratic 3 4 10–20 −0.549 .488 0.334 .672 0.806 0.78 4.264

Note. Only 1 study reported regression coefficients for MD so this measure was excluded from the meta-analysis for the anterior thalamic radiations. Boldface text indicates model with better fit according to likelihood ratio test.