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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Hepatology. 2016 Jul 17;64(5):1518–1533. doi: 10.1002/hep.28676

Figure 2. High fat diet-induced liver injury and steatosis were exacerbated in RIP3-deficient mice.

Figure 2

(A/B) Male C57BL/6 and RIP3-deficient mice (Strain containing the neomycin cassette (RIP3−/− (neo)); (C/D) Male C57BL/6 and RIP3-deficient mice (with the neomycin cassette deleted (RIP3−/− CREΔ)) and (E/F) Female C57BL/6 and RIP3-deficient mice (RIP3−/− neo) were fed HFD or chow for up to 6 or 12 weeks. (A/C/E) ALT and AST activities were measured in plasma. (B/D/F) Hepatic triglyceride content was measured in whole liver homogenate.