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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Hepatology. 2016 Jul 4;64(5):1534–1546. doi: 10.1002/hep.28659

Figure 4. Worsening of the metabolic phenotypes in adi-hRBP4 mice fed a high-fat diet.

Figure 4

(A) Weight gains for male adi-hRBP4 and littermate control mice fed a high-fat diet providing 60% of calories from fat. The values presented reflect mean percent weight gains ± SEM. (B) Liver TG levels after a 6 h fast for matched control and adi-hRBP4 mice fed a high-fat diet for 24 days (n = 4 - 6). (C) Representative cryosections of livers stained with Oil Red O in high-fat diet fed mice. Bars represent 100 μM. Total liver FFA (D) levels and plasma FFA (E) levels measured for age- and gender-matched adi-RBP4 and littermate control mice fed a high-fat diet (n = 4 - 6). (F) Acyl composition of the FFA pool within livers of matched adi-RBP4 and littermate control mice as determined by LC/MS/MS (n = 4 - 6). *, P < 0.05 versus controls (CTL).