Table 3.
Measures of urinalysis test accuracy stratified by specimen timing and how the specimen was obtained.
| Samples taken during or within 3 weeks post EBRT (N = 140) | ||||||
|---|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | DOR1 [95% CI] | P | |
| Nitrites | 32.0% | 93.1% | 72.7% | 70.4% | 6.35[2.29–17.62] | 0.000086 |
| LE | 90.0% | 28.4% | 41.7% | 83.3% | 3.57 [1.27–10.04] | 0.012 |
| Nitrites AND1 LE | 30.0% | 93.2% | 71.4% | 70.1% | 5.86 [2.10–16.34] | 0.000213 |
| Nitrites OR2 LE | 92.0% | 27.6% | 42.2% | 27.6% | 4.38 [1.42–13.49] | 0.006 |
| WBC | 91.3% | 38.8% | 46.2% | 88.6% | 6.54 [2.17–20.34] | 0.000225 |
| Nitrites AND WBC | 28.0% | 96.6% | 82.4% | 70.5% | 11.15 [3.02–41.16] | 0.000013 |
| LE and WBC | 83.7% | 50.0% | 48.2% | 84.6% | 5.13 [2.16–12.17] | 0.000072 |
| Blood | 72.0% | 35.2% | 38.7% | 68.9% | 1.4[0.66–2.98] | 0.388 |
| RBC | 72.2% | 28.4% | 35.1% | 65.5% | 1.03 [0.42–2.54] | 0.951 |
| Protein | 64.0% | 34.1% | 35.6% | 62.5% | 0.92 [0.45–1.9] | 0.823 |
| Ketones | 14.0% | 86.4% | 36.8% | 63.9% | 1.03 [0.38–2.82] | 0.953 |
| Samples taken > 3 weeks post EBRT (N =101) | ||||||
| Nitrites | 21.2% | 94.0% | 63.6% | 70.8% | 4.24 [1.14–15.75] | 0.022 |
| LE | 91.2% | 29.9% | 39.7% | 87.0% | 4.4[1.20–16.06] | 0.017 |
| Nitrites AND LE | 21.2% | 94.0% | 63.6% | 70.8% | 4.24 [1.14–15.73] | 0.022 |
| Nitrites OR LE | 91.2% | 29.9% | 39.7% | 87.0% | 4.4[1.2–16.06] | 0.017 |
| WBC | 90.3% | 29.1% | 41.8% | 84.2% | 3.83 [1.02–14.41] | 0.037 |
| Nitrites AND WBC | 21.2% | 94.0% | 63.6% | 70.8% | 4.24 [1.14–15.75] | 0.022 |
| LE and WBC | 82.4% | 44.6% | 43.8% | 82.9% | 3.72 [1.37–10.3] | 0.008 |
| Blood | 76.5% | 31.3% | 36.1% | 72.4% | 1.48 [0.58–3.82] | 0.412 |
| RBC | 83.3% | 26.5% | 35.7% | 76.5% | 1.81 [0.52–6.28] | 0.349 |
| Protein | 82.4% | 37.3% | 40.0% | 80.6% | 2.79 [1.01–7.64] | 0.043 |
| Ketones | 20.6% | 83.6% | 38.9% | 67.5% | 1.32 [0.46–3.78] | 0.605 |
| Clean catch samples (N =164) | ||||||
| Nitrites | 19.1% | 93.0% | 52.9% | 73.6% | 3.14 [1.13–8.72] | 0.023 |
| LE | 87.2% | 29.6% | 33.6% | 85.0% | 2.87 [1.11–7.39] | 0.024 |
| Nitrites AND LE | 17.0% | 93.0% | 50.0% | 73.3% | 2.74 [0.96–7.81] | 0.051 |
| Nitrites OR LE | 89.4% | 28.9% | 34.1% | 86.8% | 3.42 [1.24–9.41] | 0.013 |
| WBC | 88.1% | 35.0% | 36.3% | 87.5% | 3.99 [1.44–11.05] | 0.005 |
| Nitrites AND WBC | 17.0% | 94.8% | 57.1% | 73.8% | 1.76 [1.23–11.52] | 0.014 |
| LE and WBC | 78.3% | 49.6% | 38.7% | 84.8% | 3.54 [1.6–7.81] | 0.001 |
| Blood | 61.7% | 36.5% | 28.4% | 70.0% | 0.927 [0.46–1.87] | 0.832 |
| RBC | 73.3% | 29.9% | 26.5% | 76.5% | 1.17 [0.46–2.97] | 0.738 |
| Protein | 63.8% | 36.5% | 29.1% | 71.2% | 1.02 [0.5–2.05] | 0.966 |
| Ketones | 14.9% | 84.3% | 28.0% | 70.8% | 0.94 [0.37–1.43] | 0.903 |
| Catheter (N=76) and suprapubic (N=1) samples | ||||||
| Nitrites | 38.9% | 95.0% | 87.5% | 63.3% | 12.09 [2.51–58.23] | 0.000296 |
| LE | 94.6% | 27.5% | 54.7% | 84.6% | 6.64 [1.36–32.39] | 0.01 |
| Nitrites AND LE | 38.9% | 95.0% | 87.5% | 63.3% | 12.09 [2.51–58.23] | 0.000296 |
| Nitrites OR LE | 94.6% | 27.5% | 54.7% | 84.6% | 6.64 [1.36–32.39] | 0.01 |
| WBC | 94.3% | 34.3% | 58.9% | 85.7% | 8.61 [1.76–42.16] | 0.003 |
| Nitrites AND WBC | 36.1% | 97.5% | 92.9% | 62.9% | 22.04 [2.7–179.69] | 0.000161 |
| LE and WBC | 89.2% | 42.5% | 58.9% | 81.0% | 6.1[1.81–20.5] | 0.002 |
| Blood | 89.2% | 25.0% | 52.4% | 71.4% | 2.75 [0.78–9.7] | 0.107 |
| RBC | 80.0% | 20.7% | 51.1% | 50.0% | 1.04 [0.29–3.71] | 0.948 |
| Protein | 81.1% | 32.5% | 52.6% | 65.0% | 2.06 [0.72–5.93] | 0.175 |
| Ketones | 18.9% | 87.5% | 58.3% | 53.8% | 1.63 [0.47–5.68] | 0.438 |
PPV (positive predictive value), NPV (negative predictive value), DOR (diagnostic odds ratio), LE (leukocyte esterase), WBC (white blood cells), RBC (red blood cells).
1
Both tests positive.
2
One or both tests positive.