TABLE 3.

PZA resistance assay characteristics among 121 MDR-TB patients, using a consensus gold standard derived from an LCA model as the comparator^a

PZA resistance assay	Sensitivity (%)	Specificity (%)	AUC of ROC
Wayne method	82.4 (71.2–90.5)	92.5 (81.8–97.9)	0.87 (0.82–0.93)
MGIT	95.6 (87.6–99.1)	88.7 (77.0–95.7)	0.92 (0.87–0.97)
pncA sequencing	92.6 (83.7–97.6)	90.6 (79.3–96.9)	0.92 (0.87–0.97)

^aAUC, area under the curve; LCA, latent class analysis; MDR-TB, multidrug-resistant tuberculosis; MGIT, mycobacteria growth indicator tube; PZA, pyrazinamide; ROC, receiver operating characteristic. Values in parentheses are 95% confidence intervals.