Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Time course of plasma concentrations of efavirenz (EFV) (A), 8-hydroxy-EFV (8-OHEFV) (B), di-OHEFV (C), and 7-OHEFV (D) in healthy volunteers after a single 100-mg oral dose alone (○) or after treatment with voriconazole to steady state (●). The insets for EFV represent log-transformed concentration-time profile of EFV (A) or plasma concentration-time profiles of metabolites from 0 to 24 h (B, C, and D).
