TABLE 3.
Correlation of checkerboard test results with clinical outcomes among 18 XDR A. baumannii isolates
Parameter | Growth inhibition in any SAC well | Growth in all SAC wells | P valuea |
---|---|---|---|
No. of patients/total (%) with: | |||
Clinical cure | 4/8 (50) | 3/10 (30) | 0.63 |
Microbiological clearance | 7/8 (88) | 3/10 (30) | 0.02 |
30-day all-cause mortality | 3/8 (38) | 6/10 (60) | 0.63 |
Median APACHE II score | 20 | 20.5 | 0.29 |
Median Charlson score | 4 | 5 | 0.32 |
Median time (h) to targeted therapy | 87 | 67 | 0.23 |
Fisher's exact and Mann-Whitney U tests (GraphPad Software, Inc.) were used to compare categorical and continuous variables, respectively.