Table 1.
Promoter methylation in different types of cancer
| Cancer type | Gene | Promoter methylation | Reference |
|---|---|---|---|
| Breast | RARB2, MSH2, ESR1B, AKR1B1, COL6A2, GPX7, HIST1H3C, HOXB4, RASGRF2,TM6SF1, ARHGEF7, TMEFF2, RASSF1, BRCA1, STRATIFIN, RASSF1A | Hypermethylation | [102] |
| Gastric | RUNX3 | Hypermethylation | [102] |
| Liver | CDKN2A | Hypermethylation | [102] |
| Esophageal | APC | Hypermethylation | |
| Colorectal | SEPT9, hMLH1, CDKN2A/p16, HTLF, ALX4, TMEFF2/HPP1, NGFR, SFRP2, NEUROG1, RUNX3,UBE2Q1 | Hypermethylation | [103,104] |
| Lung | RARB2, RASSF1A, CHFR, STRATI-FIN, SHOX2, RASSF1A APC1 | Hypermethylation | [102] |