Table 1.
Patient and Case Characteristics
| Patient/Case characteristics | Did not receive neostigmine | Received neostigmine |
|---|---|---|
| Total N = 135,633 | N = 18,510 (13.6 %) | N = 117,123 (86.4 %) |
| Agea | 51 ± 18 | 52 ± 17 |
| Surgical case duration (minutes)b | 144 [87,238] | 113 [69,177] |
| Emergent surgery | 835 (4.5) | 6095 (5.2) |
| ASA status | ||
| ASA class 1 or 2 | 10,976 (59.3) | 68,910 (58.8) |
| ASA class 3 or 4 | 7534 (40.7) | 48,213 (41.2) |
| Gender | ||
| Male | 9484 (51.2) | 63,165 (53.9) |
| Female | 9026 (48.8) | 53,957 (46.1) |
| World Health Organization BMI categories | ||
| Underweight, BMI <18.5 | 481 (2.7) | 2456 (2.2) |
| Normal Weight, BMI 18.5–24.9 | 5466 (30.8) | 3,2491 (28.7) |
| Overweight, BMI 25.0–29.9 | 5509 (31.0) | 35,302 (31.2) |
| Class I Obesity, BMI 30.0–34.9 | 3346 (18.8) | 22,634 (20.0) |
| Class II Obesity, BMI 35.0–39.9 | 1645 (9.3) | 11,321 (10.0) |
| Class III Obesity, BMI ≥40 | 1326 (7.5) | 8973 (7.9) |
| Last Recorded TOF | ||
| 0/4 | 347 (1.9) | 3557 (3.0) |
| 1/4 | 478 (2.6) | 6987 (6.0) |
| 2/4 | 510 (2.8) | 7751 (6.6) |
| 3/4 | 425 (2.3) | 7170 (6.1) |
| 4/4 | 4187 (22.6) | 82,457 (70.4) |
| Undocumented | 12,563 (67.9) | 9201 (7.9) |
| Surgical service | ||
| Dental | 734 (4.0) | 2904 (2.4) |
| General | 2275 (12.3) | 20,532 (17.5) |
| Gynecology | 1000 (5.4) | 11,742 (10.0) |
| Neurology | 1937 (10.5) | 9395 (8.0) |
| Ophthalmology | 443 (2.4) | 1630 (1.4) |
| Orthopedics | 2843 (15.4) | 18,273 (15.6) |
| Other | 1296 (7.0) | 8763 (7.5) |
| Otolaryngology | 3691 (19.9) | 8452 (7.2) |
| Plastics | 1492 (8.1) | 7814 (6.7) |
| Radiology | 304 (1.6) | 2056 (1.8) |
| Thoracic | 533 (2.9) | 5754 (4.9) |
| Transplant | 419 (2.3) | 4810 (4.1) |
| Urology | 1093 (5.9) | 10,657 (9.1) |
| Vascular | 450 (2.4) | 4341 (3.7) |
| Neuromuscular blockade agentc | ||
| Atracurium | 1435 (7.8) | 4528 (3.9) |
| Cisatracurium | 3613 (19.5) | 17,892 (15.3) |
| Pancuronium | 1402 (7.6) | 657 (0.6) |
| Rocuronium | 1867 (10.1) | 7069 (6.0) |
| Vecuronium | 10,720 (57.9) | 88,526 (75.6) |
| Multiple NMBAs | 521 (2.8) | 1544 (1.3) |
| Succinylcholine with NMBA | 5891 (31.8) | 28,608 (24.4) |
ASA American Society of Anaesthesiologists, BMI body mass index, TOF train-of-four, NMBA neuromuscular blockade agent
aAge is represented as mean ± standard deviation
bSurgical case duration is non-parametric and presented as median [25th to 75th percentile]
cCases may have received more than one type of neuromuscular blocking agent