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. 2016 Oct 22;16:103. doi: 10.1186/s12871-016-0266-2

Table 4.

Subgroup analysis of individual neuromuscular blocking agents

Cases receiving neostigmine Cases not receiving neostigmine
Neuromuscular blocking agent Cases receiving NMB NMB total dose (ED 95 Equivalent)a Time between last NMB & extubation (minutes) Total dose of neostigmine (mcg/kg)b Cases receiving NMB NMB total dose (ED 95 Equivalent)a Time between last NMB & extubation (minutes)
N Median [IQR] Median [IQR] Median [IQR] N Median [IQR] Median [IQR]
No Succinylcholine Atracurium 2981 3.9 [2.6, 5.9] 67.0 [50.0, 90.0] 33.7 [29.7, 41.7] 906 2.9 [2.1, 4.7] 119.0 [85.0, 174.0]
Cisatracurium 12,905 5.6 [3.9, 8.3] 73.0 [53.0, 102.0] 36.0 [30.2, 42.4] 2596 4.6 [3.1, 7.1] 136.0 [90.0, 204.0]
Pancuronium 134 1.3 [0.1, 2.3] 99.5 [62.0, 161.0] 47.2 [35.8, 61.7] 48 0.1 [0.1, 0.1] 210.5 [150.5, 265.0]
Rocuronium 5602 2.8 [2.2, 4.0] 83.0 [59.0, 117.0] 36.6 [29.8, 41.7] 1510 2.4 [1.8, 3.4] 126.0 [89.0, 174.0]
Vecuronium 65,708 3.4 [2.4, 4.9] 76.0 [55.0, 108.0] 38.2 [31.5, 42.2] 7343 2.8 [2.0, 4.5] 145.0 [93.0, 233.0]
Multiple NMBAs 1185 5.9 [4.4, 8.0] 71.0 [52.0, 101.0] 39.0 [32.1, 44.9] 216 6.6 [4.8, 8.6] 92.0 [37.5, 162.5]
Succinylcholine Atracurium 1407 3.4 [2.2, 5.4] 60.0 [46.0, 84.0] 31.8 [28.2, 39.0] 439 2.5 [1.5, 4.4] 95.0 [65.0, 141.0]
Cisatracurium 4591 4.8 [2.9, 7.6] 65.0 [49.0, 88.0] 32.7 [28.8, 40.0] 864 4.1 [2.2, 7.5] 106.0 [68.0, 153.0]
Pancuronium 63 2.1 [1.2, 2.6] 96.0 [74.0, 140.0] 37.0 [31.6, 48.0] 1025 0.1 [0.1, 0.1] 101.5 [60.0, 181.5]
Rocuronium 674 2.1 [1.3, 3.0] 62.0 [42.0, 87.0] 32.1 [26.1, 39.4] 232 1.0 [0.3, 2.0] 81.0 [53.0, 129.0]
Vecuronium 21,514 3.0 [1.9, 4.7] 67.0 [49.0, 93.0] 36.7 [30.0, 41.3] 3026 2.6 [1.3, 4.8] 115.0 [67.0, 195.0]
Multiple NMBAs 359 3.6 [2.2, 5.6] 65.0 [46.0, 94.0] 35.1 [30.0, 41.3] 305 3.0 [1.5, 6.3] 82.0 [41.0, 154.0]

aOnly among patients with IBW between 40 and 250 kg

bOnly among patients with TBW between 40 and 250 kg