Table 4.
Predictor of HOMA index at study completion by unadjusted and multivariable adjusted linear regression analyses
| Predictor of HOMA index at study completion | |||
|---|---|---|---|
| Variable | B-coef | Standard Error | P value |
| Unadjusted | |||
| - Treatment (yes vs no) | −0.8740 | 0.3285 | 0.0087 |
| Unadjusted | |||
| - Change in serum bicarbonate (%) | −1.5833 | 0.9462 | 0.0964 |
| Unadjusted | |||
| - Serum bicarbonate at study completion (mmol/l) | −0.14511 | 0.06026 | 0.0173 |
| Adjusted for treatment, change in serum bicarbonate and interaction of change in serum bicarbonate*treatment | |||
| - Treatment (yes vs no) | −1.4604 | 0.5015 | 0.00418 |
| - Change in serum bicarbonate (%) | −3.0382 | 1.8007 | 0.09378 |
| - Interaction test (change in serum bicarbonate*treatment) | 4.9948 | 2.3578 | 0.03591 |
| Adjusted for treatment, serum bicarbonate at follow-up and interaction of serum bicarbonate at followup*treatment | |||
| - Treatment (yes vs no) | −11.6700 | 4.4255 | 0.00931 |
| - Serum bicarbonate at follow-up (mmol/l) | −0.2328 | 0.1106 | 0.03713 |
| - Interaction test (serum bicarbonate at follow-up*treatment) | 0.4476 | 0.1784 | 0.01325 |
*interaction between factors