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. 2016 Oct 22;16:400. doi: 10.1186/s12906-016-1393-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effect of methanol extract of C. cristata in hot plate test. Data are presented as the mean ± SEM (n = 5). MECC = Methanol extract of C. cristata; NLX = Naloxone. * represents p < 0.001 compared with the control group (Dunnett’s test). ^{a, b, c, d, e} represents p < 0.001, compared with the MECC 50, MECC 100, MECC 200, MECC 400, morphine, group respectively (Bonferroni’s test)