Table 2.
Effect of oral administration of MECC on gross changes to the vital organs of mice
| Treatment | Organ weight (g) (Organ body index in %) |
|||||
|---|---|---|---|---|---|---|
| Body weight | Heart | Kidneys | Liver | Lungs | Spleen | |
| Vehicle | 22.04 ± 0.25 | 0.15 ± 0.01 (0.66) | 0.38 ± 0.01 (1.72) | 1.32 ± 0.02 (6.01) | 0.23 ± 0.02 (1.03) | 0.10 ± 0.01 (0.46) |
| MECC (1000 mg/kg) | 21.28 ± 0.16 | 0..11 ± 0.01 (0.52) | 0.32 ± 0.02 (1.48) | 1.33 ± 0.13 (6.23) | 0.18 ± 0.01 (0.86) | 0.07 ± 0.01 (0.35) |
| MECC (2000 mg/kg) | 23.39 ± 0.48 | 0.18 ± 0.01 (0.79) | 0.44 ± 0.03 (1.85) | 1.79 ± 0.12 (7.78) | 0.27 ± 0.02 (1.14) | 0.15 ± 0.02 (0.63) |
| MECC (4000 mg/kg) | 23.27 ± 0.58 | 0.17 ± 0.01 (0.89) | 0.41 ± 0.03 (1.74) | 1.76 ± 0.19 (7.52) | 0.29 ± 0.04 (1.23) | 0.14 ± 0.02 (0.60) |
Each value is presented as the mean ± SEM (n = 5). MECC = Methanol extract of C. cristata, organ body index (%) = (weight of organ/weight of body)/100. P is not ≤ 0.05, compared to control group (Dunnett’s test)