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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Neuropharmacology. 2016 Sep 13;111:323–334. doi: 10.1016/j.neuropharm.2016.09.013

Figure 5. Effect of nicotine on visceral pain in C57BL/6 (B6) and BTBR mice.

Figure 5

Box plots show median, interquartile range, and 5th and 95th percentiles for number of writhes after acetic acid intraperitoneal injection in B6 (white) and BTBR (gray) mice. P values indicate comparisons between treatments (nicotine 0 or 100µg/ml) within respective strains. Nicotine-treated B6 and BTBR mice had significantly less writhes than saccharine-treated respective controls (p<0.001 for B6 and p=0.007 for BTBR). N=14 (age matched balanced number of male and female) mice per group. † indicates p≤0.01, and ‡ p≤0.001.