Table 4.
Mean values for all analytes in the three groups of subjects.
Analyte (1ng/mL, 2pg/mL, 3 µg/mL) | Mean | ||
---|---|---|---|
Group 1 | Group 2 | Group 3 | |
Metabolomic markers | |||
Malondialdehyde1 | 22.1 | 32.3 | 31.2 |
4-Hydroxyhexenal1 | 13.1 | 29.4 | 28.9 |
4-Hydroxynonenal1 | 23.9 | 33.3 | 35.8 |
Hexanal1 | 15.4 | 28.3 | 24.2 |
Heptanal1 | 22.5 | 32.1 | 28.9 |
Oktanal1 | 9.0 | 15.1 | 13.6 |
Nonanal1 | 12.2 | 15.3 | 14.6 |
Decanal1 | 9.0 | 13.8 | 12.6 |
Undodecanal1 | 5.6 | 7.2 | 6.9 |
Dodecanal1 | 6.6 | 8.1 | 7.5 |
3-Nitrotyrosine2 | 52.5 | 76.4 | 74.6 |
8-Hydroxy-2′-deoxyguanosine2 | 190.2 | 341.8 | 303.3 |
8-Hydroxyguanosine2 | 190.2 | 337.9 | 284.1 |
5-Hydroxymethyluracil2 | 90.1 | 168.0 | 156.8 |
o-Tyrosine2 | 54.6 | 91.4 | 82.6 |
3-Chlortyrosine2 | 23.8 | 50.2 | 44.5 |
Leukotriene B4 2 | 151.3 | 381.2 | 293.1 |
8-Isoprostane2 | 20.5 | 43.4 | 38.6 |
Leukotriene E4 2 | 120.0 | 135.5 | 126.0 |
Leukotriene D4 2 | 55.6 | 65.1 | 62.8 |
Leukotriene C4 2 | 63.9 | 76.4 | 71.6 |
Proteomic markers | |||
Interleukin 62 | 38.8 | 110.5 | 78.8 |
Interleukin 82 | 18.3 | 97.4 | 60.6 |
Monocyte chemotactic protein-11 | 1.6 | 5.2 | 4.9 |
Epidermal growth factor1 | 5.1 | 2.9 | 3.2 |
α1-Antitrypsin1 | 16.0 | 55.0 | 40.6 |
IgA-Uromodulin1 | 53.8 | 518.0 | 221.9 |
Galactose-deficient IgA11 | 49.8 | 186.7 | 141.3 |
Soluble transferrin receptor1 | 10.0 | 41.2 | 37.5 |
LG3 fragment of endorepellin1 | 14.0 | 53.2 | 63.9 |
Tumstatin2 | 72.5 | 158.5 | 167.8 |
Endostatin2 | 75.2 | 192.7 | 178.1 |
Heparan sulfate3 | 0.1 | 2.1 | 1.1 |
Group 1 (healthy controls), group 2 (IgAN patients), and group 3 (disease controls, patients with membranous nephropathy, lupus nephritis, antineutrophilic cytoplasmic antibody vasculitis-associated kidney disease, or diabetic nephropathy).