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Week 96 results from Phase 3 randomised trials of first-line tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate (TDF) [23]
| Treatment arms: | TAF/FTC/EVG/c | TDF/FTC/EVG/c |
|---|---|---|
| (n=866) | (n=867) | |
| HIV RNA <50 copies/mL | 87% | 85% |
| Virological failure | 5% | 5% |
| Drug resistance | 1.2% | 0.9% |
| Grade 3 or 4 clinical adverse events | 12% | 12% |
| Grade 3 or 4 laboratory adverse events | 28% | 25% |
c: cobicistat; EVG: elvitegravir; FTC: emtricitabine; TAF: tenofovir alafenamide; TDF: tenofovir disoproxil fumarate.
