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. 2016 Oct 22;11:141. doi: 10.1186/s13014-016-0715-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The variation trends of four kinds of ADC histogram parameters during concurrent chemo-radiotherapy (CCRT) in patients with cervical cancers. a, b Skewness and kurtosis show a quick and significant decrease from pre-CCRT to the end of 4th week of CCRT. c, d First-order entropy and entropy(H)_mean show no significant early change followed by a progressive and remarkable decrease after 2nd week of CCRT. *: P < 0.05. time point 1: before CCRT; time point 2: at the end of 2nd week of CCRT; time point 3: at the end of 4th week of CCRT; time point 4: immediately after CCRT completion