Table 1.
Demographic, Clinical, Laboratory and Treatment Characteristics of Study Patients with Acute Myocardial Infarction, further stratified by Atrial Fibrillation Status
| Characteristics | Incident AF (n=693) | Prevalent AF (n=493) | No AF (n=5,198) | P value in relation to No AF |
|---|---|---|---|---|
| Age -Mean [SD] | 76.2 [11.4] | 79.8 [8.9] | 68.5 [14.5] | <0.001 |
| Age < 65 years | 15.7 % | 5.9 % | 38.1 % | <0.001 |
| Age 65–84 years | 55.8 % | 54.4 % | 44.7 % | <0.001 |
| Age >= 85 years | 28.4 % | 39.8 % | 17.3 % | <0.001 |
| Sex, % Men | 50.8 % | 54.4 % | 56.6% | 0.01 |
| White Race | 91.5 % | 94.5 % | 89.1 % | <0.001 |
| Angina Pectoris | 13.7 % | 18.3 % | 15 % | 0.08 |
| Chronic Kidney Disease | 21.9 % | 31.4 % | 17.7 % | <0.001 |
| COPD | 20.2 % | 26.4 % | 16.9 % | <0.001 |
| Diabetes | 33.2 % | 36.3 % | 33.8 % | 0.48 |
| Heart failure | 24.4 % | 48.9 % | 22.5 % | <0.001 |
| Hyperlipidemia | 52.4 % | 50.9 % | 56.6 % | <0.001 |
| Hypertension | 74.5 % | 81.3 % | 71.1 % | <0.001 |
| Stroke | 12.5 % | 20.1 % | 11.1 % | <0.001 |
| AMI Type | ||||
| ST-segment elevation myocardial infarction | 38.1 % | 20.5 % | 35.4 % | <0.001 |
| Non ST-segment elevation Myocardial infarction | 61.9 % | 79.5 % | 64.6 % | <0.001 |
| Initial AMI | 70.9 % | 53.5 % | 64.6 % | <0.001 |
| Q Wave | 26.3% | 10.5 % | 21.9 % | <0.001 |
| Non Q Wave | 73.7 % | 89.5 % | 78.1% | <0.001 |
| Troponin I Peak in ng/mL – Mean [SD] | 28.1 [83.3] | 17.9 [44.4] | 18.1 [66.9] | <0.001 |
| Creatinine in mg/dl - Mean [SD] | 1.5 [1.1] | 1.6 [1] | 1.4 [1.1] | <0.001 |
| Factors at Admission | ||||
| Initial Heart Rate (bpm)-Mean [SD] | 91.6 [27.3] | 91.6 [24.2] | 84.9 [21.1] | <0.001 |
| Systolic Blood Pressure (mmHg) - Mean [SD] | 133.5 [31.9] | 134.7 [31.5] | 142.5 [31.3] | <0.001 |
| Diastolic Blood Pressure (mmHg)- Mean [SD] | 73.7 [19.4] | 73[18.4] | 77.8 [19.5] | <0.001 |
| Respiratory Rate (per minute)- Mean [SD] | 21.9 [6.3] | 22.1 [5.9] | 21 [5.5] | <0.001 |
| In-Hospital Medications | ||||
| Beta-blocker | 85.6 % | 86.8 % | 88.1 % | 0.13 |
| Aspirin | 90.0 % | 85.2 % | 91.9 % | <0.001 |
| Statin/Lipid Lowering Agents | 63.5 % | 55.8 % | 69 % | <0.001 |
| ACE-I/ARB | 62.5 % | 59.6 % | 62.6 % | 0.4 |
| Clopidogrel | 49.6 % | 37.3 % | 58.9 % | <0.001 |
| Calcium Channel Blockers | 33.2 % | 34.9 % | 19.1 % | <0.001 |
| Diuretic | 67.1 % | 75.7 % | 46.4 % | <0.001 |
| Digoxin | 34.1 % | 44.2 % | 10.9 % | <0.001 |
| Thrombolytics | 4.4 % | 2.0% | 6.3 % | <0.001 |
| Enoxaparin/Heparin | 27.1 % | 18.3 % | 19.8 % | <0.001 |
| Warfarin | 19.9 % | 40.8 % | 8.4 % | <0.001 |
| In-Hospital Procedures | ||||
| Percutaneous coronary Intervention | 37.2 % | 21.5 % | 44.8 % | <0.001 |
| Cardiac Catheterization | 48.1 % | 34.5 % | 59.5 % | <0.001 |
Note: All values are mean +- SD or % unless otherwise noted.
ACE-I/ARB= Angiotensin converting enzyme inhibitor/Angiotensin receptor blocker
AMI= Acute myocardial infarction
COPD= Chronic obstructive pulmonary disease
SD= Standard deviation