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. Author manuscript; available in PMC: 2016 Oct 23.
Published in final edited form as: Sci Transl Med. 2015 Dec 2;7(316):316ra195. doi: 10.1126/scitranslmed.aad0966

Figure 3. The binary combination of hu1B7 and hu11E6 is synergistic and more potent than P-IVIG in vitro.

Figure 3

The CHO cell clustering assay was used to determine the molar ratio of antibodies to PTx required for complete neutralization of CHO morphology changes. A, Different ratios of hu1B7 and hu11E6 were compared to determine the most potent ratio. B, An equimolar ratio of humanized 1B7 and 11E6 was compared to the same ratio of murine antibodies and P-IVIG. Results depict average of three replicate experiments; statistical significance determined by single-factor ANOVA and Tukey’s test with a=0.05.