Table 3.
SUVRs for various cerebral regions in one carrier of the A431E PSEN1 mutation with SP relative to 4 PSEN1 mutation carriers without SP.
| Subject with spastic paraparesis (AJ) | 4 subjects without spastic paraparesis | |
|---|---|---|
| Mean cortical binding potential | 0.21 | 0.84 (0.42) |
| Mean left posterior cingulate cortex (s.d.) | 1.46 | 2.57 (0.72) |
| Mean right posterior cingulate cortex (s.d.) | 1.58 | 2.36 (0.76) |
| Mean left primary visual cortex (s.d.) | 1.52 | 2.20 (0.73) |
| Mean right primary visual cortex (s.d.) | 1.50 | 2.06 (0.59) |
| Mean left sensorimotor cortex (s.d.) | 1.06 | 1.97 (0.30) |
| Mean right sensorimotor cortex (s.d.) | 1.15 | 1.99 (0.34) |
| Mean left thalamus (s.d.) | 1.72 | 1.93 (0.65) |
| Mean right thalamus (s.d.) | 1.86 | 2.00 (0.49) |
| Mean left caudate nucleus (s.d.) | 1.21 | 2.02 (0.65) |
| Mean right caudate nucleus (s.d.) | 1.08 | 2.07 (0.52) |
| Mean reft cerebellum (s.d.) | 1.00 | 1.02 (0.00) |
| Mean right cerebellum (s.d.) | 0.99 | 0.98 (0.00) |