Fig. 5.
Single mitochondrial flashes detected in Langendorff perfused heart. (A) Representative images of the intact myocardium showing the colocalization of mt-cpYFP and TMRM. Scale bar = 20 µm. (B) Image of a single cardiomyocyte in the intact myocardium. The area highlighted by the white boxes is enlarged to show a mitochondrial flash accompanied with decrease in membrane potential (white arrows). Scale bars = 20 and 5 µm for the full size and enlarged images, respectively. (C) Traces showing the fluorescence changes during the single mitochondrial flash highlighted in (B).