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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Neurobiol Aging. 2016 Jul 15;47:1–9. doi: 10.1016/j.neurobiolaging.2016.07.006

Figure 5. Increased IL-1β gene expression in 5-aza and LPS-treated primary cultured microglia coincides with decreased IL-1β promoter DNA methylation.

Figure 5

Primary cultured microglia were treated with 5-aza for 24 h and/or LPS for 4 h. Bars represent the mean ± SEM (n = 3–4) for A) IL-1β promoter DNA methylation as measured by a Methylation Index (MI) and B) IL-1β mRNA expression.