Table 3a.
Percentage difference in DXA-derived and pQCT-derived outcomes for a 5-year difference (diff) in age at menarche , additionally adjusted for current height and weight, smoking and adult social class, women
| Unadjusted |
Adjusted for height & weight |
Additionally adjusted for smoking and adult social class |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. | % diff | 95% CI | P-value | % diff | 95% CI | P-value | % diff | 95% CI | P-value | |
| pQCT measures | ||||||||||
| pQCT-cortical sites | ||||||||||
| 50% radius | ||||||||||
| Diaphysis CSA (mm2) | 567 | −2.5 | −7.1, 2.12 | 0.3 | −3.3 | −7.5, 1.0 | 0.1 | −3.3 | −7.6, 0.9 | 0.1 |
| Medullary CSA (mm2) | 565 | 0.8 | −10.4, 12 | 0.9 | −2.2 | −13.4, 8.9 | 0.7 | −2.5 | −13.7, 8.7 | 0.7 |
| Polar stress strain index (mm3) | 568 | −4.1 | −10.6, 2.5 | 0.2 | −4.9 | −11.1, 1.2 | 0.1 | −4.9 | −11.1 to1.3 | 0.1 |
| pQCT-trabecular sites | ||||||||||
| Distal radius (4%) | ||||||||||
| Distal CSA (mm2) | 562 | 3.6 | −2.7, 9.9 | 0.3 | 2.0 | −4.1, 8.0 | 0.5 | 2.1 | −3.9, 8.2 | 0.5 |
| pQCT-50% radius | ||||||||||
| Cortical vBMD (mg/cm3) | 568 | 0.2 | −0.9, 1.4 | 0.7 | 0.4 | −0.8, 1.5 | 0.5 | 0.4 | −0.7, 1.6 | 0.5 |
| pQCT-distal radius (4%) | ||||||||||
| Trabecular vBMD (mg/cm3) | 561 | −11 | −19.3, -2.5 | 0.01 | −8.0 | −16.6, 0.5 | 0.07 | −8.1 | −16.7, 0.5 | 0.07 |
| Total density vBMD (mg/cm3) | 562 | −8 | −15.1, -0.9 | 0.03 | −5.5 | −12.7, 1.7 | 0.1 | −5.7 | −12.9, 1.5 | 0.1 |
| DXA measures | ||||||||||
| DXA aBMD (g/cm2) | ||||||||||
| Spine L1-L4 aBMD | 695 | −7.2 | −12.4, -2.1 | 0.006 | −4.8 | −9.9, 0.3 | 0.06 | −4.8 | −9.9, 0.3 | 0.06 |
| Total hip aBMD | 691 | −8.2 | −12.6, -3.8 | < 0.001 | −4.3 | −8.3, −0.3 | 0.04 | −4.2 | −8.1 to−0.1 | 0.04 |