Table 3b.

Percentage difference in DXA-derived and pQCT-derived outcomes comparing pre-adolescent with fully mature males at 14.5 years, additionally adjusted for current height and weight, smoking and adult social class, men

		Unadjusted			Adjusted for height & weight			Additionally adjusted for smoking and adult social class
	No.	% diff	95% CI	P-value	% diff	95% CI	P-value	% diff	95% CI	P-value
pQCT measures
pQCT-cortical sites
50% radius
Diaphysis CSA (mm2)	542	−5.0	−8.7, -1.2	0.009	−3.8	−7.1, −0.4	0.03	−3.8	−7.1, −0.5	0.03
Medullary CSA (mm2)	541	−9.9	−18.6, -1.3	0.02	−8.4	−16.8, −0.02	0.05	−8.5	.03	0.046
Polar stress strain index (mm3)	538	−6.1	−11.4, -0.8	0.02	−4.3	−9.0, 0.5	0.08	−4.4	−9.0, 0.3	0.07
pQCT-trabecular sites
Distal radius (4%)
Distal CSA (mm2)	542	−2.7	−8.1, 2.7	0.3	−1.8	−7.1, 3.5	0.5	−1.7	−6.9, 3.6	0.5
pQCT-50% radius
Cortical vBMD (mg/cm3)	542	0.9	0.1, 1.7	0.02	0.8	0.1, 1.6	0.04	0.8	0.02, 1.6	0.04
pQCT-distal radius (4%)
Trabecular vBMD (mg/cm3)	541	−9.2	−14.7, -3.8	0.001	−8.9	−14.4, −3.5	0.001	−9.2	−14.6 to−3.7	0.001
Total density vBMD (mg/cm3)	542	−1.5	−6.0, 3.1	0.5	−1.3	−5.9, 3.2	0.6	−1.6	−6.1, 3.0	0.5
DXA measures
DXA aBMD (g/cm2)
Spine L1-L4 aBMD	647	−4.5	−8.5, -0.4	0.03	−2.7	−6.4, 1.1	0.2	−2.6	−6.4, 1.2	0.2
Total hip aBMD	640	−4.5	−8.0, -1.0	0.01	−2.5	−5.6, 0.7	0.1	−2.6	−5.7, 0.5	0.1