Table 3.
Effect of Bacopa monnieri (300 mg/day) on neuropsychological tests (mean scores ± SD).
| Neuropsychological task | Bacopa group | Placebo group | “p” value | ||
|---|---|---|---|---|---|
| (n = 28) | (n = 14) | ||||
| Before drug | After drug | Before drug | After drug | ||
| Digit span forwards | 7.23 ± 1.11 | 7.85 ± 0.83 | 7.83 ± 1.19 | 7.73 ± 0.23 | >0.05 |
| Digit span backwards | 8.1 ± 1.3 | 8.3 ± 0.9 | 9.1 ± 1.0 | 8.3 ± 0.8 | <0.05∗ |
| Paired associate task | 8 ± 1.3 | 7.7 ± 1.4 | 8.1 ± 1.1 | 7.9 ± 1.3 | >0.05 |
| Logical memory test | 3.4 ± 2.6 | 5.2 ± 4.5 | 5.5 ± 2.6 | 4.1 ± 3.8 | <0.05∗ |
| Memory span for nonsense syllables | 5.4 ± 3.3 | 6.9 ± 2.4 | 4.7 ± 2.3 | 6.1 ± 2.9 | >0.05 |
| Finger tapping test | 152.28 ± 15.75 | 154.56 ± 13.71 | 157.60 ± 14.89 | 158.48 ± 27.89 | >0.05 |
| Simple reaction time | 221.88 ± 53.17 | 221.01 ± 52.16 | 213.13 ± 33.6 | 212.49 ± 33.62 | >0.05 |
| Choice reaction time | 350.07 ± 52.08 | 340.03 ± 62.26 | 342.39 ± 67.54 | 340.95 ± 64.45 | >0.05 |
| Choice discrimination test | 383.70 ± 52.54 | 387.06 ± 53.47 | 374.02 ± 51.46 | 379.44 ± 58.32 | >0.05 |
| Digit picture substitution test | 1492.69 ± 368.58 | 1467.78 ± 556.55 | 1465.94 ± 293.94 | 1325.44 ± 207.07 | >0.05 |
∗On comparing Bacopa group with placebo group by using unpaired Student's “t”-test.