Table 2.
Markers of oxidative stress and antioxidants in women with GDM and without GDM (controls).
| GDM | Controls | |||||
|---|---|---|---|---|---|---|
| 16–20 weeks | 24–28 weeks | 32–36 weeks | 16–20 weeks | 24–28 weeks | 32–36 weeks | |
| PCO (ng/mL) | 172.77 ± 13.59∗ | 200.77 ± 19.23 | 232.48 ± 21.93∗ | 136.82 ± 10.05 | 169.09 ± 13.10 | 180.81 ± 11.57 |
| AOPPs (μmol/L) | 64.74 ± 1.39∗ | 74.92 ± 1.67△ | 83.59 ± 1.87△ | 59.98 ± 1.54 | 65.83 ± 1.57 | 72.86 ± 1.34 |
| 8-iso-PGF2α (ng/mL) | 196.14 ± 16.78∗ | 356.96 ± 40.10 | 538.72 ± 67.36∗ | 154.82 ± 9.89 | 289.74 ± 22.68 | 381.07 ± 37.26 |
| GPX-3 (μIU/mL) | 160.42E3 ± 13.76E3∗ | 68.29E3 ± 8.50E3 | 35.65E3 ± 2.90E3# | 83.71E3 ± 25.58E3 | 44.590E3 ± 3.49E3 | 26.46E3 ± 1.46E3 |
| PON1 (mIU/mL) | 162.88E3 ± 22.12E3∗ | 136.18E3 ± 20.98E3 | 97.00E3 ± 5.51E3 | 260.20E3 ± 28.89E3 | 165.77E3 ± 18.92E3 | 115.59E3 ± 25.73E3 |
Data are means ± SD. # P < 0.01 versus controls. ∗ P < 0.05 versus controls. △ P < 0.001 versus controls. There was no significance in PCO (P = 0.12), 8-iso-PGF2α (P = 0.09), GPX-3 (P = 0.23), and PON1 (P = 0.35) in 24–28 weeks compared to the control group. Meanwhile, in 32–36 weeks, no significance was found in PON1 (P = 0.56) compared to the controls.