Figure 1.

Ngo inhibits IL-1β levels in culture supernatants from infected MDM but is not able to inhibit IL-1β mRNA expression. MDM cells were infected with Ngo and then cytokine and RNA levels were evaluated after 30 minutes after infection. (a) Detection of IL-1β in culture supernatant by ELISA. (b) Transcriptional cytokine analysis by qRT-PCR. Results represent fold changes in transcript levels between no infected MDM and MDM infected with Ngo or treated with LPS. Data obtained are expressed as the mean ± SD and represent at least 6 independent experiments. ^∗ P < 0.05; ^∗∗∗∗ P < 0.0001.