Table 1.
Transcriptional activation of inflammasome-associated genes in MDM.
| Gene designation |
Protein | Fold changea | |
|---|---|---|---|
| MDM+Ngo | MDM+Ngo+ATP | ||
| NLRP3 | NLR family, pyrin domain- containing protein 3 |
0.67 | 3.45† |
| ASC | Apoptosis-associated speck-like protein containing a caspase recruitment domain |
0.54 | 0.63 |
| CASP1 | Caspase-1 | 2.1 | 2.6 |
aValues represent fold changes in transcript levels between MDM infected with Neisseria gonorrhoeae and MDM infected with Neisseria gonorrhoeae treated with ATP. † P < 0.05. Mann–Whitney U test.