Table 5.
Clinical features in bilateral Meniere disease according to the onset of hearing loss.
| Variables | Synchronic (n = 103) | Metachronic (n = 291) | p-value |
|---|---|---|---|
| Age, mean (SD) | 61 (11.0) | 60.1 (11.9) | 0.49 |
| Gender (% women) | 63 (61.2) | 161 (55.3) | 0.36 |
| Age of onset (SD) | 46.1 (12.8) | 43.5 (13.2) | 0.07 |
| Age of onset ≤40, n (%) | 39 (37.9) | 118 (40.5) | 0.73 |
| Time course (years), mean (SD) | 14.4 (8.9) | 16.2 (8.9) | 0.08 |
| Family history, n (%) | 39 (39.8) | 119 (43.0) | 0.64 |
| FMD, n (%) | 11 (13.3) | 40 (17.7) | 0.39 |
| Hearing loss at diagnosis, mean (SD) | 55.1 (17.0) | 55.9 (17.0) | 0.71 |
| Headache, n (%) | 55 (53.4) | 96 (33.3) | 0.0004 |
| Migraine, n (%) | 25 (24.3) | 49 (17.0) | 0.11 |
| Rheumatoid history, n (%) | 15 (15.0) | 35 (12.2) | 0.49 |
| Hearing stage, n (%) | |||
| 1 | 1 (1.0) | 6 (2.1) | 0.004 |
| 2 | 27 (26.5) | 34 (11.7) | |
| 3 | 42 (41.2) | 152 (52.4) | |
| 4 | 32 (31.4) | 98 (33.8) | |
| Cardiovascular risk | |||
| High blood pressure, n (%) | 47 (51.1) | 109 (39.9) | 0.068 |
| Dyslipidemia, n (%) | 53 (55.2) | 121 (45.1) | 0.097 |
| Type 2 diabetes, n (%) | 13 (13.5) | 50 (18.5) | 0.35 |
| Smoking, n (%) | 22 (21.8) | 68 (24.5) | 0.68 |
| Tumarkin crisis, n (%) | 24 (25.8) | 69 (24.9) | 0.89 |
| Functional Scale, n (%) | |||
| 1 | 14 (14.0) | 73 (26.0) | 0.11 |
| 2 | 29 (29.0) | 77 (27.4) | |
| 3 | 26 (26.0) | 55 (19.6) | |
| 4 | 12 (12.0) | 40 (14.2) | |
| 5 | 16 (16.0) | 27 (9.6) | |
| 6 | 3 (3.0) | 9 (3.2) | |
Significant p values in bold.