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. 2016 Oct;5(5):399–407. doi: 10.21037/hbsn.2016.08.05

Table 2. Risk factors associated with hepatocellular carcinoma recurrence.

Variables Univariate analysis Multivariate analysis
P value HR (95% CI) P value
Pretransplant factor
   Pre-treatment therapies 0.4200
   Tumor number ≥2 0.0900
   Tumor size ≥2.0 cm 0.0400
   Within Milan criteria 0.0400
   Within Tokyo criteria 0.0001 0.08 (0.01–0.66) 0.0141
   Alpha-fetoprotein ≥400 ng/mL <0.0001 11.00 (2.09–58.41) 0.0047
   Des-gamma-carboxy prothrombin ≥200 mAU/mL 0.0010 6.20 (1.31–29.45) 0.0217
   Graft type; right/left 0.6100
   Graft volume to standard liver volume ≥40% 0.8300
Posttransplant factor
   Tumor number ≥2 0.0700
   Tumor size ≥2.0 cm 0.3400
   Within Milan criteria 0.5700
   Within Tokyo criteria 0.9300
   Microvascular invasion 0.0040

CI, confidence interval; HR, hazard ratio.