Skip to main content
. 2016 Oct;5(5):422–428. doi: 10.21037/hbsn.2016.08.03

Table 1. Studies comparing living donor liver transplantation (LDLT) and deceased donor liver transplantation (DDLT) for hepatocellular carcinoma (HCC).

Author LDLT vs. DDLT Country Year Study period Type of LT Case number Recurrence free survival Criteria used Outside Milan (%) Difference in tumor characteristics Median follow-up period (months)
1-year 3-year 5-year P
Hu et al. (15) LDLT > DDLT China 2015 1999−2009 LDLT 389 78 64 62 <0.001 Hangzhou criteria 6 More aggressive in DDLT 16
DDLT 6,471 66 49 42 4 15
Ninomiya et al. (16) LDLT = DDLT Japan (LDLT); USA (DDLT) 2015 2002−2010 LDLT 133 92 86 85 NS Kyushu criteria 41 More aggressive in LDLT 76
DDLT 362 94 86 81 Milan 34 67
Xiao et al. (17) LDLT = DDLT China 2014 1999−2012 LDLT 84 85 56 53 NS Hangzhou criteria 69 None 27
DDLT 276 73 49 45 72
Park et al. (18) LDLT < DDLT Korea 2014 1999−2010 LDLT 166 89 81 0.045 UCSF NA None 35
DDLT 50 96 94
Sandhu et al. (19) LDLT = DDLT Canada 2013 1996−2009 LDLT 58 88 75 70 NS Toronto criteria 28 None 38
DDLT 287 86 75 70 32 31
Kulik et al. (20) LDLT < DDLT USA 2012 1998−2010 LDLT 100 80 66 56 0.05 UNOS 59 More aggressive in LDLT 60
Multi-center DDLT 97 90 81 73 30
Bhangui et al. (10) LDLT = DDLT France 2011 2000−2009 LDLT 36 100 89 88 NS UCSF 27 None 58
DDLT 120 93 89 86 21 50
Li et al. (14) LDLT = DDLT China 2010 2005−2009 LDLT 38 71 42 NS UCSF 79 None 25
DDLT 101 76 41 68
Di Sandro et al. (13) LDLT = DDLT Italy 2009 2000−2007 LDLT 25 96 96 NS Milan 20 None
DDLT 154 91 89 31
Sotiropoulos et al. (21) LDLT = DDLT Germany 2007 1998−2006 LDLT 45 88 75 NS UCSF 44 None
DDLT 55 81
Lo et al. (22) LDLT < DDLT Hong Kong 2007 1995−2004 LDLT 43 93 71 71 0.029 UCSF 26 More aggressive in LDLT 33
DDLT 17 100 100 100 29
Hwang et al. (23) LDLT = DDLT Korea 2005 1992−2002 LDLT 237 83 80 NS 27 None 26
Multi-center DDLT 75 88 82 29 45
Gondolesi et al. (3) LDLT = DDLT USA 2004 1988−2002 LDLT 36 82 74 NS UNOS 53 None 15
DDLT 165 90 83

DDLT, deceased donor liver transplantation; HCC, hepatocellular carcinoma; LDLT, living donor liver transplantation; LT, liver transplantation; UCSF, the University of California, San Francisco; UNOS, United Network for Organ Sharing