Table 4.
NASA univariate analysis of predictors of 90-day functional outcomes
| mRS score ≤2 (n = 132) | mRS score >2 (n = 183) | p | |
|---|---|---|---|
| Demographics | |||
| Mean age ± SD, years | 65.0±15.1 | 69.2±14.4 | 0.02 |
| Females | 69 (52.7) | 95 (51.9) | 0.89 |
| Mean baseline NIHSS (range) | 15 (12–20) | 19 (16–24) | <0.0001 |
| White ethnicity | 101 (77.7) | 132 (72.5) | 0.54 |
| Comorbidities | |||
| Hypertension | 95 (72.0) | 146 (79.8) | 0.11 |
| Atrial fibrillation | 52 (39.4) | 83 (45.4) | 0.29 |
| Diabetes mellitus | 27 (20.5) | 50 (27.3) | 0.16 |
| Hyperlipidemia | 63 (47.7) | 101 (55.2) | 0.19 |
| Smoking history | 42 (32.1) | 53 (29.3) | 0.60 |
| Coronary artery disease | 40 (30.3) | 63 (34.4) | 0.44 |
|
| |||
| Clinical presentation | |||
| Occlusion site | 0.06 | ||
| MCA-M1 | 81.0 (61.4) | 90.0 (49.5) | |
| ICA | 23.0 (17.4) | 53 (29.1) | |
| Vertebrobasilar | 12 (9.1) | 22 (12.1) | |
| Mean initial systolic blood pressure ± SD, mm Hg | 140.3±25.5 | 148.6±28.6 | 0.01 |
| Mean initial diastolic blood pressure ± SD, mm Hg | 76.7±15.6 | 79.9±18.8 | 0.10 |
| IV rt-PA | 70 (53.0) | 65 (35.7) | 0.002 |
| Procedural factors | |||
| Mean TOG ± SD, min | 338.7±229.1 | 384.6±251.6 | 0.10 |
| Mean time to revascularization or end of procedure ± SD, min | 59.4±70.5 | 79.9±79.8 | 0.03 |
| General anesthesia | 62.0 (60.2) | 113 (75.8) | 0.008 |
| IA rt-PA | 34.0 (25.8) | 56.0 (30.6) | 0.35 |
| Use of balloon guide catheter | 65.0 (51.2) | 61.0 (35.5) | 0.007 |
| Mean number of passes ± SD | 1.5 (0.84) | 2.0 (1.1) | <0.0001 |
| Use of rescue therapy | 16.0 (12.1) | 65.0 (35.5) | <0.0001 |
| Imaging outcomes | |||
| mTICI ≥2a | 127 (96.2) | 153.0 (83.6) | 0.0004 |
| mTICI ≥2b | 118.0 (89.4) | 115.0 (63.2) | <0.0001 |
| sICH | 3.0 (2.3) | 29.0 (16.0) | <0.0001 |
Values are n (%) unless otherwise indicated. Values in italics indicate statistical significance.