Table 2.
List of backbone genes in Exophiala dermatitidis involved in the production of secondary metabolites.
| Gene | Type | Comment (fold, fdr) |
|---|---|---|
| DMATS | HMPREF1120_00352 | (4.11, 0.009) |
| HMPREF1120_01260 | (2.86, 0.026) | |
| HMPREF1120_01968 | ||
| HMPREF1120_02200 | ||
| HMPREF1120_06543 | ||
| HMPREF1120_07933 | ||
| HMPREF1120_08032 | ||
| HMPREF1120_08132 | ||
| HMPREF1120_09268 | ||
| HMPREF1120_09269 | ||
| HMPREF1120_08670 | (3.55, 0.011) | |
| HMPREF1120_09038 | (3.20, 0.008) | |
| HMPREF1120_09090 | ||
| NRPS | HMPREF1120_01440 | |
| HMPREF1120_02993 | Acetylaranotin, toxin | |
| HMPREF1120_04809 | ||
| HMPREF1120_06043 | (7.511, 0.0045) | |
| HMPREF1120_07636 | (2.46, 0.033) | |
| NRPS-like | HMPREF1120_00598 | (13.55, 0.005) |
| HMPREF1120_03318 | ||
| HMPREF1120_07093 | ||
| PKS | HMPREF1120_03173 | |
| HMPREF1120_06568 | ||
| HMPREF1120_06570 | t1PKS | |
| HMPREF1120_07394 | t3PKS | |
| PKS-Like | HMPREF1120_08091 | |
| TERPENE | HMPREF1120_02863 | |
| HMPREF1120_03149 | Terpene Cyclase (3.46, 0.012) | |
| HMPREF1120_09198 | (3.11, 0.008) |
Exophiala dermatitidis genome contains 13 DMATS, 8 NRPS/NRPS-like, 3 TERPENE and 8 PKS/PKS-like backbone genes. 4 DMATS, 2 terpene and 3 NRPS/NRPS-like backbone-enzymes were upregulated during skin invasion.