Figure 3.

GSEA of identified genes required for neural cell death. The expression data are ranked in the order of differential expression. A, Forty-seven core enrichment factors from the siRNA library screen for DNA damage–induced cell death genes classified by GSEA analysis. B, Five individual plots (p-value <0.05) of the running sum for the gene sets in the ranked gene list. C, Subcellular localization was categorized using the top 80 genes from the siRNA library screen. Genes with no annotations were excluded from the analysis.