Table 5.
Measurements of mucosal proteins by ELISA
Protein | IBS-D (n = 15) | Control Patients (n = 6) | Estimated Sample Size per Group to Observe 2.5-Fold Difference in Protein Concentration, Based on Pooled SD of Each Protein |
---|---|---|---|
INADL | 9.39 (2.68, 25.74) | 5.83 (2.9, 23.2) | 30 |
MAGI1 | 0.83 (0.00, 2.75) | 0.79 (0.00, 2.26) | 13 |
MAPKAPK5 | 0.54 (0.04, 1.96) | 0.73 (0.00, 1.60) | 15 |
PGK1 | 4.17 (3.71, 4.53) | 4.38 (3.69, 4.83) | Housekeeping gene |
Data are median and interquartile range (IQR); all comparisons are not statistically significant; PGK1 is the housekeeping gene. There was insufficient mucosa for protein measurements in 1 control patient. SD, standard deviation.