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. 2016 Jul 28;311(3):G377–G386. doi: 10.1152/ajpgi.00124.2016

Fig. 7.

Fig. 7.

Inhibition of TNF decreases liver injury in knockout (KO) mice. Control (Con) and KO mice were pretreated 4 h before LPS administration with an isotypic IgG control antibody or a monoclonal IgG2a against mouse TNF and killed at 24 h for analysis of serum ALT levels (*P < 0.03, compared with KO mice treated with control antibody; n = 7–9; A); TUNEL staining (*P < 0.001, compared with KO mice treated with control antibody; n = 4–8; B); and histological grade of liver injury (*P < 0.04, compared with KO mice treated with control antibody; n = 4–8; C). Values are means ± SE.